Description

1-Bromo-2,5-Dichloro-4-Methoxybenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of bromine, chlorine, and methoxy substituents into complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where its substitution pattern confers specific biological activity.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and advanced polymers due to its electron-withdrawing halogen groups.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, leveraging the reactive bromine atom.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments where halogen atoms influence color and stability.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	1-Bromo-2,5-Dichloro-4-Methoxybenzene
CAS No.	55026-90-9
Molecular Formula	C7H5BrCl2O
Molecular Weight	256.93 g/mol
Synonyms	2,5-Dichloro-4-methoxybromobenzene; 4-Bromo-2,5-dichloroanisole; Benzene, 1-bromo-2,5-dichloro-4-methoxy-; 2,5-Dichloro-1-bromo-4-methoxybenzene; 1-Bromo-2,5-dichloro-4-methoxy-benzene; Bromo-dichloro-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,5-Dichloro-4-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary packaging or amber glass/vessels for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.