Description

Acetylshikonin CAS NO 54984-93-9 is a bioactive naphthoquinone derivative, a key constituent of the traditional medicinal plant *Lithospermum erythrorhizon* (Zicao). This compound is valued for its significant pharmacological properties, including potent anti-inflammatory, antimicrobial, and antitumor activities. It serves as a critical raw material and reference standard for the pharmaceutical, nutraceutical, and advanced cosmetic industries, where consistent purity and reliable supply are paramount for research, development, and high-value formulation.

Application

• Pharmaceutical Intermediates & APIs: Serves as a key building block or active pharmaceutical ingredient (API) in formulations targeting inflammation, microbial infections, and certain cancers.
• Reference Standards & Analytical Reagents: Used as a high-purity certified reference material (CRM) for quality control, method validation, and quantification in herbal medicine and pharmaceutical analysis.
• Cosmeceutical & Skincare Actives: Incorporated into premium skincare products for its anti-inflammatory and antioxidant properties, helping to soothe skin and combat signs of aging.
• Biomedical & Life Science Research: Employed in biochemical and pharmacological studies to investigate mechanisms of action, signaling pathways, and potential therapeutic applications.
• Natural Health Products & Nutraceuticals: Utilized as a standardized extract component in dietary supplements aimed at supporting immune function and overall wellness.
• Veterinary Pharmaceutical Applications: Applied in the development of treatments for inflammatory conditions and infections in animals.

Basic Information

Product Name	Acetylshikonin
CAS No.	54984-93-9
Molecular Formula	C18H18O6
Molecular Weight	330.33 g/mol
Synonyms	Acetylshikonin; 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]naphthalene-1,4-dione acetate; Shikonin acetate; β,β-Dimethylacrylshikonin; NSC 106399; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)-1,4-naphthoquinone 8-acetate; 1,4-Naphthoquinone, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-, 8-acetate
EINECS	Contact for details

Quality Control

Our Acetylshikonin is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep away from excessive heat and moisture. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Reddish-brown to purple crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0% (Standard Grade) ≥98.0% (High Purity Grade)
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.