Description

2-Pyrrolidinecarboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci) is a specialized N-tert-butyl protected pyrrolidine aldehyde derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a sterically hindered, protected amine functionality that is essential for constructing complex molecular architectures with high stereochemical control. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of protease inhibitors, neurological agents, and other complex drug molecules.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and organocatalysts for stereoselective transformations.
• Agrochemical Synthesis: Building block for developing novel pesticides and herbicides with specific stereochemistry.
• Peptidomimetics Research: Core structure for designing and synthesizing peptide analogs and conformationally restricted scaffolds.
• Material Science: Intermediate for creating specialized polymers and functional materials with tailored properties.
• Academic & Process R&D: Valuable reagent for methodological development and scale-up studies in organic chemistry.

Basic Information

Product Name	2-Pyrrolidinecarboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci)
CAS No.	54969-26-5
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	1-(tert-Butyl)pyrrolidine-2-carboxaldehyde; N-tert-Butyl-2-formylpyrrolidine; 1-tert-Butyl-2-pyrrolidinecarboxaldehyde; N-Boc-pyrrolidine-2-carboxaldehyde (common misnomer); 2-Formyl-1-(1,1-dimethylethyl)pyrrolidine; Pyrrolidine-2-carboxaldehyde, N-tert-butyl derivative; 1-(1,1-Dimethylethyl)-2-pyrrolidinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxaldehyde, 1-(1,1-Dimethylethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.