Description

4-Oxo-4-Phenyl-2-Butynoic Acid Ethyl Ester is a high-purity, versatile chemical intermediate characterized by its unique acetylene and keto-ester functional groups. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for applications requiring precise molecular control.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with acetylene or aryl ketone moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Organic Synthesis Reagent: Employed in cycloaddition reactions, Sonogashira couplings, and as a Michael acceptor in complex molecule assembly.
• Chemical Biology Probe Development: Utilized as a scaffold or labeling agent in the creation of molecular probes for biochemical research.

Basic Information

Product Name	4-Oxo-4-Phenyl-2-Butynoic Acid Ethyl Ester
CAS No.	54966-47-1
Molecular Formula	C12H10O3
Molecular Weight	202.21 g/mol
Synonyms	Ethyl 4-oxo-4-phenyl-2-butynoate; 4-Phenyl-4-oxo-2-butynoic acid ethyl ester; Ethyl 2-butynoate, 4-oxo-4-phenyl-; Ethyl (4-oxo-4-phenylbut-2-ynoate); Acetylene carboxylic acid ester derivative
EINECS	Contact for details

Quality Control

Our 4-Oxo-4-Phenyl-2-Butynoic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.