Description

2-Butanone, 1-Bromo-1-Fluoro- is a halogenated derivative of butanone, serving as a versatile and reactive building block in advanced chemical synthesis. This compound is valued for its ability to introduce both bromine and fluorine atoms into target molecules, enabling the creation of complex structures with modified properties. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated and brominated active pharmaceutical ingredients (APIs), particularly in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides where halogen atoms enhance biological activity and environmental stability.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to construct complex organic frameworks in research and development.
• Material Science Precursor: Acts as a starting material for synthesizing specialty polymers, liquid crystals, and advanced materials with specific electronic or surface properties.
• Fluorination Reagent: Serves as a source of fluorine in the synthesis of organofluorine compounds, which are important in various high-performance applications.

Basic Information

Product Name	2-Butanone, 1-Bromo-1-Fluoro-
CAS No.	54867-88-8
Molecular Formula	C4H6BrFO
Molecular Weight	169.00 g/mol
Synonyms	1-Bromo-1-fluoro-2-butanone; 1-Bromo-1-fluorobutan-2-one; 2-Butanone, 1-bromo-1-fluoro-; 1-Fluoro-1-bromo-2-butanone; α-Bromo-α-fluorobutan-2-one; Butan-2-one, 1-bromo-1-fluoro-; 1-Bromo-1-fluoro-2-oxobutane
EINECS	Contact for details

Quality Control

Our 2-Butanone, 1-Bromo-1-Fluoro- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its nature as a strong acid/organic solvent and highly volatile compound, appropriate secondary containment and vapor control measures are recommended.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.