Description

(S)-(+)-5-Oxotetrahydrofuran-2-Carboxylic Acid is a high-purity chiral building block and key intermediate in organic synthesis. This compound is valued for its defined stereochemistry, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), particularly in protease inhibitor and antiviral drug development.
• Asymmetric Synthesis: Serves as a versatile starting material or precursor in stereoselective reactions to construct complex molecular architectures.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is essential.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and catalysis within university and industrial research laboratories.
• Polymer Chemistry: Can be utilized as a monomer or modifier for synthesizing functionalized, biodegradable polymers.

Basic Information

Product Name	(S)-(+)-5-Oxotetrahydrofuran-2-Carboxylic Acid
CAS No.	54848-33-8
Molecular Formula	C5H6O4
Molecular Weight	130.10 g/mol
Synonyms	(S)-(+)-Tetrahydro-5-oxo-2-furancarboxylic acid; (S)-5-Oxotetrahydrofuran-2-carboxylic acid; L-(+)-Tetrahydro-5-oxo-2-furancarboxylic acid; (S)-2-Carboxy-γ-butyrolactone; (S)-γ-Carboxy-γ-butyrolactone; (2S)-5-Oxooxolane-2-carboxylic acid; (S)-5-Oxo-2-tetrahydrofurancarboxylic acid
EINECS	Contact for details

Quality Control

Our (S)-(+)-5-Oxotetrahydrofuran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical assay, and impurity profiling, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.