Description

(4S)-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One is a chiral, dihydroxylated tetralone derivative that serves as a crucial synthetic intermediate and building block in advanced organic chemistry. Its defined stereochemistry and functional group array make it valuable for constructing complex molecular architectures with high precision. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of novel, stereochemically-defined pesticides and herbicides.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and natural product analog research.
• Flavor & Fragrance Precursor: Potential intermediate in the synthesis of complex aroma chemicals.

Basic Information

Product Name	(4S)-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One
CAS No.	54712-38-8
Molecular Formula	C₁₀H₁₀O₃
Molecular Weight	178.18 g/mol
Synonyms	(4S)-4,8-Dihydroxy-1,2,3,4-tetrahydronaphthalen-1-one; (S)-4,8-Dihydroxy-3,4-dihydro-1(2H)-naphthalenone; (S)-4,8-Dihydroxy-1-tetralone; 4,8-Dihydroxy-1-tetralone (S-enantiomer); (S)-4,8-Dihydroxy-α-tetralone; 54712-38-8; (4S)-4,8-Dihydroxy-3,4-dihydronaphthalen-1(2H)-one
EINECS	Contact for details

Quality Control

Our (4S)-4,8-Dihydroxy-3,4-Dihydronaphthalene-1(2H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.