Description

12-Deoxyphorbol 13-Phenylacetate 20-Acetate is a high-purity, semi-synthetic derivative of the phorbol diterpene family, known for its specific biological activity profile. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its role as a key intermediate or reference standard. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in oncology, dermatology, and signal transduction pathway studies. The product is supplied with full analytical documentation to ensure research integrity and reproducibility.

Application

• Pharmaceutical Research: Serves as a critical intermediate or reference standard in the synthesis and development of novel therapeutic agents.
• Biological Studies: Used as a potent and specific biochemical tool to study protein kinase C (PKC) modulation and related cellular signaling pathways.
• Oncology Research: Investigated for its effects on cell proliferation, apoptosis, and tumor promotion mechanisms in experimental models.
• Dermatological Research: Applied in studies related to skin inflammation, cell differentiation, and topical drug action.
• Chemical Biology: Employed as a molecular probe to elucidate complex biological interactions and validate drug targets.
• Analytical Standard: Used as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	12-Deoxyphorbol 13-Phenylacetate 20-Acetate
CAS No.	54662-30-5
Molecular Formula	C36H42O8
Molecular Weight	602.72 g/mol
Synonyms	12-Deoxyphorbol 13-phenylacetate 20-acetate; 12-Deoxyphorbol 13-phenylacetate-20-acetate; 20-Acetoxy-12-deoxyphorbol 13-phenylacetate; NSC 268504; 12-Deoxyphorbol-13-phenylacetate-20-acetate; Phorbol 13-phenylacetate 20-acetate (12-deoxy-); 12-Deoxyphorbol-13-phenylacetate-20-acetate
EINECS	Contact for details

Quality Control

Every batch of 12-Deoxyphorbol 13-Phenylacetate 20-Acetate is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Comprehensive analytical characterization, including HPLC, NMR, and MS, is performed to confirm identity and purity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.