Description

4-Acetyl-5-Oxohexanoic Acid is a versatile keto-acid derivative with a reactive β-keto ester-like structure, making it a valuable synthon in organic synthesis. Its bifunctional nature allows it to serve as a key building block for constructing complex heterocyclic and pharmaceutical intermediates. This compound is particularly relevant for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific acetyl and carboxylic acid functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted pyridine or pyrrole rings.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its reactivity to form heterocyclic active components.
• Fine Chemical Building Block: Employed in organic synthesis for the preparation of complex molecules, dyes, and functional materials via condensation and cyclization reactions.
• Research & Development: Serves as a standard or starting material in academic and industrial research for methodological studies in ketone and acid chemistry.
• Chemical Synthesis: Acts as a versatile reagent for Claisen-type condensations and Michael addition reactions to create new carbon-carbon bonds.

Basic Information

Product Name	4-Acetyl-5-Oxohexanoic Acid
CAS No.	54605-46-8
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	5-Oxo-4-acetylhexanoic Acid; 4-Acetyl-5-oxo-hexanoic Acid; 4-Acetyllevulinic Acid; 4-Acetyl-δ-oxohexanoic Acid; 4-Acetyl-5-oxocaproic Acid; 4-Acetyl-5-ketohexanoic Acid; 4-Acetyl-5-oxo-n-caproic Acid; 4-Acetyl-5-oxohexanoate
EINECS	Contact for details

Quality Control

Our 4-Acetyl-5-Oxohexanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.