Description

p-Iodobenzylchloride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its primary value lies in its dual functional groups, which allow it to act as a key electrophilic intermediate for the introduction of the iodobenzyl moiety. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to construct complex molecules for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and cancer.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in research and diagnostic applications.
• Custom Synthesis: A fundamental reagent for contract research organizations (CROs) and fine chemical companies performing bespoke synthetic routes.

Basic Information

Product Name	p-Iodobenzylchloride
CAS No.	54589-53-6
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	1-(Chloromethyl)-4-iodobenzene; 4-Iodobenzyl Chloride; (4-Iodophenyl)methyl Chloride; p-Iodobenzyl Chloride; α-Chloro-4-iodotoluene; 4-Iodobenzylchloride; 4-Iodophenylmethyl Chloride; Iodobenzyl Chloride
EINECS	Contact for details

Quality Control

Our p-Iodobenzylchloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept tightly sealed in a dry environment and opened under inert atmosphere for prolonged handling to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.