Description

Potassium Tri-sec-Butylborohydride is a highly reactive and selective organoborohydride reducing agent, commonly known as K-Selectride®. This powerful reagent is valued for its exceptional steric bulk, which enables highly stereoselective reductions of ketones and aldehydes, particularly favoring the formation of less hindered alcohols. It is an essential tool for synthetic organic chemists in research and development, as well as in process chemistry for the production of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Stereoselective Reduction: Primary application for the selective reduction of sterically hindered ketones to produce specific alcohol stereoisomers.
• Pharmaceutical Intermediate Synthesis: Key reagent in the synthesis of complex drug molecules and chiral building blocks where precise stereochemical control is required.
• Fine Chemical Manufacturing: Used in the production of specialty chemicals, flavors, fragrances, and agrochemical intermediates.
• Academic & Industrial R&D: A staple reducing agent in laboratory-scale research for method development and exploring new synthetic pathways.
• Hydroboration Agent: Can be employed in hydroboration reactions of alkenes, followed by oxidation to yield alcohols.
• Catalyst and Ligand Modification: Used to reduce metal complexes or modify ligands in catalyst preparation.

Basic Information

Product Name	Potassium Tri-sec-Butylborohydride
CAS No.	54575-49-4
Molecular Formula	C12H28BK
Molecular Weight	222.26 g/mol
Synonyms	K-Selectride®; Potassium Tri(sec-butyl)borohydride; Potassium Tri-sec-butylboranuide; Potassium Tri-secondary-butylborohydride; Potassium Tris(2-butyl)borohydride; Borate(1-), tri(1-methylpropyl)hydro-, potassium; Potassium hydrotri(sec-butyl)borate
EINECS	Contact for details

Quality Control

Our Potassium Tri-sec-Butylborohydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. The product undergoes rigorous analytical testing, including assay by titration and impurity profiling. Certificates of Analysis (COA) detailing purity, concentration (typically in solution), and other critical parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile and easily oxidized compound, it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for solutions to maintain stability and potency. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizing agents, and water/moisture.

Specification

Item	Specification
Appearance	Colorless to slightly yellow solution
Concentration (Typical)	1.0 M in THF or other specified solvent
Assay (by Titration)	≥ 95.0%
Identification (IR)	Conforms
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.