Description

Jolkinolide E CAS NO 54494-34-7 is a specialized diterpenoid lactone compound, a member of the lathyrane class, known for its distinct chemical structure and biological activity. This compound is valued in research and development for its role as a key intermediate and a bioactive reference standard. It is primarily sought by professionals in the pharmaceutical, biotechnology, and natural product chemistry sectors for applications in drug discovery, phytochemical analysis, and as a building block for more complex synthetic derivatives.

Application

• Pharmaceutical Research: Serves as a crucial reference standard and intermediate in the development of novel therapeutic agents, particularly in anti-cancer and anti-inflammatory drug discovery programs.
• Natural Product Chemistry: Used as a purified marker compound for the identification, quantification, and quality control of plant extracts from the *Euphorbia* genus and related species.
• Biochemical Studies: Employed in pharmacological and biological assays to investigate its mechanism of action, cytotoxicity, and interaction with specific cellular targets.
• Academic & Institutional Research: A vital reagent for universities and research institutes conducting studies on diterpenoid biosynthesis, structure-activity relationships (SAR), and natural product isolation.
• Fine Chemical Synthesis: Acts as a sophisticated starting material or intermediate for the semi-synthesis of more complex diterpenoid analogs with enhanced or modified biological properties.

Basic Information

Product Name	Jolkinolide E
CAS No.	54494-34-7
Molecular Formula	C₂₀H₂₈O₄
Molecular Weight	332.43 g/mol
Synonyms	Jolkinolide E; 3,12-Dioxo-7,13(16),14-lathyratrien-15,20-olide; Euphorbia factor Je1; (5β,6α,7α,11α)-7,20-Epoxy-3,12-dioxolathyra-13(16),14-dien-15-one; Lathyrane diterpenoid; 54494-34-7
EINECS	Contact for details

Quality Control

Our Jolkinolide E is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.