Description

1-O,2-o-(Methylboranediyl)-3-O,5-o-(Methylboranediyl)-α-D-Xylofuranose is a specialized organoboron derivative of xylofuranose, characterized by its unique bicyclic methylboronate structure. This compound is valued for its role as a key chiral intermediate and protecting group in sophisticated synthetic organic chemistry, particularly for carbohydrate and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in the synthesis of novel bioactive molecules, boron neutron capture therapy (BNCT) agents, and complex glycoconjugates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of boron-containing drug candidates and prodrugs.
• Carbohydrate Chemistry: Used as a protecting group for cis-diols in sugar molecules, enabling selective functionalization during complex oligosaccharide synthesis.
• Nucleoside & Nucleotide Analog Synthesis: Employed in the preparation of modified nucleosides with potential antiviral or anticancer activity.
• Boron Neutron Capture Therapy (BNCT) Research: Investigated as a precursor for developing tumor-targeting boron delivery agents.
• Asymmetric Synthesis: Acts as a chiral auxiliary or template in stereoselective reactions due to its rigid, defined stereochemistry.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying carbohydrate-protein interactions and metabolic pathways.

Basic Information

Product Name	1-O,2-o-(Methylboranediyl)-3-O,5-o-(Methylboranediyl)-α-D-Xylofuranose
CAS No.	54400-96-3
Molecular Formula	C7H13BO5
Molecular Weight	187.99 g/mol
Synonyms	α-D-Xylofuranose, 1,2:3,5-bis-O-(methylboranediyl)-; 1,2:3,5-Bis-O-(methylboranediyl)-α-D-xylofuranose; α-D-Xylofuranose 1,2:3,5-bis(methylboronate); Methylboronic anhydride derivative of α-D-xylofuranose; Xylofuranose bis(methylboronate); 1,2:3,5-Di-O-methylboranyl-α-D-xylofuranose
EINECS	Contact for details

Quality Control

Our production of 1-O,2-o-(Methylboranediyl)-3-O,5-o-(Methylboranediyl)-α-D-Xylofuranose adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.