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Methyl 3-O,4-o-(Methylboranediyl)-2-o-(Trimethylsilyl)-6-Deoxy-α-L-Galactopyranoside CAS NO 54400-92-9


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CAS No.:54400-92-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 3-O,4-o-(Methylboranediyl)-2-o-(Trimethylsilyl)-6-Deoxy-α-L-Galactopyranoside is a sophisticated, high-purity carbohydrate derivative featuring a unique boronate ester and silyl ether protecting group combination. This compound is specifically engineered as a critical intermediate in advanced organic synthesis, offering precise control over stereochemistry and reactivity. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biochemical sectors for the development of novel therapeutics, complex glycoconjugates, and diagnostic agents.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of complex carbohydrate-based drugs, nucleoside analogs, and targeted therapeutic agents.
  • Glycochemistry Research: Used in the study and synthesis of oligosaccharides, glycopeptides, and other biologically active glycomolecules.
  • Protecting Group Strategy: The methylboranediyl and trimethylsilyl groups serve as orthogonal protecting groups for selective functionalization in multi-step synthetic routes.
  • Bioconjugation: Enables the site-specific modification of proteins, peptides, and other biomolecules for drug delivery and diagnostic applications.
  • Chemical Biology Probes: Acts as a precursor for creating molecular probes to study carbohydrate-protein interactions and enzymatic processes.
  • Process Development: Serves as a high-value intermediate in the scale-up and optimization of synthetic pathways for active pharmaceutical ingredients (APIs).

Basic Information

Product Name Methyl 3-O,4-o-(Methylboranediyl)-2-o-(Trimethylsilyl)-6-Deoxy-α-L-Galactopyranoside
CAS No. 54400-92-9
Molecular Formula C12H25BO5Si
Molecular Weight 288.22 g/mol
Synonyms Methyl 3,4-O-(Methylboranediyl)-2-O-(trimethylsilyl)-6-deoxy-α-L-galactopyranoside; 6-Deoxy-α-L-galactopyranoside, methyl 3,4-O-(methylboranediyl)-2-O-(trimethylsilyl)-; Methyl 2-O-trimethylsilyl-3,4-O-methylboranediyl-6-deoxy-α-L-galactopyranoside; TMS-protected methyl galactoside boronate ester; α-L-Galactopyranoside derivative, methylboranediyl-TMS protected; Carbohydrate boronate ester intermediate; Methyl 6-deoxy-2-O-TMS-3,4-O-methylboranediyl-α-L-galactopyranoside
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Quality Control

Our production of this advanced synthetic intermediate adheres to stringent quality assurance protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and MS to ensure structural integrity and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and bases.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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