Description

4-(2-Chloroethoxy)Benzaldehyde is a versatile aromatic aldehyde derivative characterized by a chloroethoxy side chain, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in its bifunctional reactivity, where the aldehyde group and the chloroalkyl chain provide distinct handles for sequential chemical modifications, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for synthesizing active pharmaceutical ingredients (APIs), liquid crystal compounds, and specialized polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those with benzodioxane or related heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its aromatic-aldehyde functionality.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of liquid crystal compounds for display technologies (LCDs) due to its rigid aromatic core and flexible ether linkage.
• Polymer & Resin Modifier: Employed to introduce aldehyde functional groups into polymer chains, enhancing cross-linking capabilities or providing sites for further conjugation.
• Organic Synthesis Reagent: Acts as a versatile starting material for palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and condensation reactions to form chalcones or imines.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and organic pigments where the aldehyde group is crucial for chromophore formation.

Basic Information

Product Name	4-(2-Chloroethoxy)Benzaldehyde
CAS No.	54373-15-8
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	p-(2-Chloroethoxy)benzaldehyde; 4-(2-Chloroethoxy)benzaldehyde; Benzaldehyde, 4-(2-chloroethoxy)-; 1-Chloro-2-(4-formylphenoxy)ethane; 4-Formylphenoxyethyl chloride; (4-Formylphenoxy)ethyl chloride; 2-(4-Formylphenoxy)ethyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Chloroethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, GC for residual solvent analysis, and IR/NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.