Description

3-Cyclopropylbenzonitrile is a versatile aromatic nitrile derivative featuring a cyclopropyl substituent, serving as a critical building block in advanced organic synthesis. Its unique structure provides a rigid, three-membered ring system that is valuable for modulating the physicochemical properties of target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the cyclopropyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers requiring specific aromatic nitrile functionalities.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, photoaffinity labels, and other molecular probes for biochemical research.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	3-Cyclopropylbenzonitrile
CAS No.	54134-94-0
Molecular Formula	C10H9N
Molecular Weight	143.19 g/mol
Synonyms	3-Cyanophenylcyclopropane; m-Cyclopropylbenzonitrile; Benzonitrile, 3-cyclopropyl-; (3-Cyanophenyl)cyclopropane; 3-Cyclopropylphenyl cyanide; Cyclopropyl-m-benzonitrile; m-(Cyclopropyl)benzonitrile; 1-Cyano-3-cyclopropylbenzene
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.