Description

n-2',4',6'-Trimethoxyphenacyl Bromide is a specialized organic bromide compound, recognized as a valuable building block and reagent in advanced synthetic chemistry. Its core value lies in its role as a photoremovable protecting group (PRPG) precursor, enabling precise, light-triggered deprotection in sensitive synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule synthesis.

Application

• Photolabile Protecting Group Precursor: Key intermediate for synthesizing caged compounds and photoremovable protecting groups (e.g., for carboxylic acids, phosphates).
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) requiring light-sensitive functional group manipulation.
• Agrochemical Synthesis: Serves as a building block for creating novel crop protection agents and herbicides with specific release mechanisms.
• Biochemical Research: Employed in the synthesis of probes and tools for studying biological processes with spatial and temporal control via photolysis.
• Advanced Materials Chemistry: Utilized in the development of photo-responsive polymers, surfaces, and smart materials.
• Organic Synthesis Reagent: Acts as an alkylating agent or a precursor to phenacyl derivatives in multi-step synthetic routes.

Basic Information

Product Name	n-2',4',6'-Trimethoxyphenacyl Bromide
CAS No.	54109-15-8
Molecular Formula	C11H13BrO4
Molecular Weight	289.12 g/mol
Synonyms	2-Bromo-1-(2,4,6-trimethoxyphenyl)ethanone; α-Bromo-2',4',6'-trimethoxyacetophenone; 2,4,6-Trimethoxyphenacyl bromide; 2-Bromo-2',4',6'-trimethoxyacetophenone; Trimethoxyphenacyl bromide; TMPhABr; 54109-15-8
EINECS	Contact for details

Quality Control

Our n-2',4',6'-Trimethoxyphenacyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to consistent quality and supply chain reliability supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.