Description

2-Bromo-1-(2,3,4-Trimethoxy-Phenyl)-Ethanone is a versatile brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a reactive bromoacetyl group adjacent to a trimethoxyphenyl ring, makes it a critical precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the trimethoxyphenyl moiety is a common bioactive component.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its electron-rich aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic and Industrial Research: Utilized in methodological studies and for exploring new chemical reactions, such as cross-coupling and cyclization reactions.

Basic Information

Product Name	2-Bromo-1-(2,3,4-Trimethoxy-Phenyl)-Ethanone
CAS No.	54109-14-7
Molecular Formula	C11H13BrO4
Molecular Weight	289.12 g/mol
Synonyms	2-Bromo-1-(2,3,4-trimethoxyphenyl)ethanone; 2-Bromo-2',3',4'-trimethoxyacetophenone; 2',3',4'-Trimethoxy-2-bromoacetophenone; 1-(2,3,4-Trimethoxyphenyl)-2-bromoethanone; α-Bromo-2,3,4-trimethoxyacetophenone; NSC 403121; Ethanone, 2-bromo-1-(2,3,4-trimethoxyphenyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We adhere to a quality management system to ensure traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.