Description

Dimethyl [2-Oxo-3-[3-(Trifluoromethyl)Phenoxy]Propyl]Phosphonate is a specialized organophosphorus compound featuring a trifluoromethylphenoxy moiety, making it a valuable synthon in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for phosphonate-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that require specific phosphonate ester functionalities.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Dimethyl [2-Oxo-3-[3-(Trifluoromethyl)Phenoxy]Propyl]Phosphonate
CAS No.	54094-19-8
Molecular Formula	C12H14F3O5P
Molecular Weight	326.21 g/mol
Synonyms	Dimethyl (2-oxo-3-(3-(trifluoromethyl)phenoxy)propyl)phosphonate; Phosphonic acid, P-[2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]-, dimethyl ester; 3-(3-(Trifluoromethyl)phenoxy)-2-oxopropylphosphonic acid dimethyl ester; α-Oxo-β-(3-trifluoromethylphenoxy)propylphosphonic acid dimethyl ester; CAS 54094-19-8
EINECS	Contact for details

Quality Control

Our Dimethyl [2-Oxo-3-[3-(Trifluoromethyl)Phenoxy]Propyl]Phosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.