Description

2-Bromo-5-Methyl-1,3,4-Thiadiazole is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive bromine substituent and the electron-deficient thiadiazole ring, making it a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

2-Bromo-5-Methyl-1,3,4-Thiadiazole serves as a crucial synthetic intermediate. Its primary applications include:

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those with thiadiazole-based scaffolds exhibiting biological activity.
• Agrochemical Synthesis: A key building block for creating advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole moiety.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and electronic materials due to its unique heterocyclic structure.
• Organic Synthesis & Research: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions for introducing the 5-methyl-1,3,4-thiadiazole unit.
• Ligand and Complex Preparation: Useful for synthesizing specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Bromo-5-Methyl-1,3,4-Thiadiazole
CAS No.	54044-79-0
Molecular Formula	C3H3BrN2S
Molecular Weight	178.03 g/mol
Synonyms	5-Methyl-2-bromo-1,3,4-thiadiazole; 2-Bromo-5-methyl-1,3,4-thiadiazole; 1,3,4-Thiadiazole, 2-bromo-5-methyl-; 5-Methyl-1,3,4-thiadiazol-2-yl bromide; Bromo-methylthiadiazole; 2-Bromo-5-methyl-[1,3,4]thiadiazole; Methylbromothiadiazole
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methyl-1,3,4-Thiadiazole is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.