Description

Desogestrel is a synthetic progestogen belonging to the gonane class, widely recognized for its high selectivity and potency. It serves as a key active pharmaceutical ingredient (API) in modern hormonal contraceptives and hormone replacement therapies. This compound is essential for manufacturers in the global pharmaceutical industry seeking reliable, high-purity intermediates for finished dosage forms.

Application

• Pharmaceutical API: Primary use as the active progestogen component in combined oral contraceptive pills.
• Hormone Replacement Therapy (HRT): Used in formulations to manage menopausal symptoms in combination with estrogen.
• Progestin-Only Contraceptives: A critical ingredient in progestin-only pills (POPs or "mini-pills").
• Drug Intermediate: Serves as a high-purity chemical intermediate in the synthesis of more complex steroid molecules.
• Research & Development: Used in biochemical and pharmacological research to study progesterone receptor activity.

Basic Information

Product Name	Desogestrel
CAS No.	54024-22-5
Molecular Formula	C22H30O
Molecular Weight	310.48 g/mol
Synonyms	13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol; Org 2969; 11-Methylene-17α-ethynyl-17β-hydroxy-18-methyl-19-nor-4-androsten-3-one; 17α-Ethynyl-11-methylene-17β-hydroxy-18-methyl-19-nor-4-androsten-3-one; 3-Oxo-11-methylene-17α-ethynyl-17β-hydroxy-18-methyl-19-nor-4-androstene
EINECS	Contact for details

Quality Control

Our Desogestrel is manufactured under strict quality management systems, targeting specifications that meet or exceed major pharmacopoeial standards such as USP and EP. Each batch undergoes comprehensive analytical testing including HPLC for assay and related substances, residual solvent analysis, and identity confirmation. A Certificate of Analysis (COA) documenting full compliance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water (Karl Fischer)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.