Description

1-(2-Trifluoromethylphenyl)-2-Nitroethylene is a specialized organic intermediate featuring a nitroethylene moiety attached to a trifluoromethyl-substituted aromatic ring. This compound matters for its unique reactivity profile, making it a valuable building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries seeking to introduce fluorinated aromatic systems into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Used in the development of advanced organic materials, including liquid crystals and organic semiconductors, where its electronic properties are exploited.
• Fluorine Chemistry: An essential reagent for studying and introducing fluorinated aromatic structures into complex molecular architectures.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments requiring nitro and fluorinated components.

Basic Information

Product Name	1-(2-Trifluoromethylphenyl)-2-Nitroethylene
CAS No.	53960-62-6
Molecular Formula	C9H6F3NO2
Molecular Weight	217.15 g/mol
Synonyms	2-Nitro-1-[2-(trifluoromethyl)phenyl]ethene; (E)-1-(2-(Trifluoromethyl)phenyl)-2-nitroethene; 2-(Trifluoromethyl)benzalnitromethane; α-(2-Trifluoromethylphenyl)-β-nitroethylene; 2-Trifluoromethyl-β-nitrostyrene; β-Nitro-2-(trifluoromethyl)styrene; 1-(2-Trifluoromethylphenyl)-2-nitroethene; (2-Trifluoromethylphenyl)nitroethylene
EINECS	Contact for details

Quality Control

Our 1-(2-Trifluoromethylphenyl)-2-Nitroethylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.