Description

4,5-Dihydro-5-Thioxothiophen-2(3H)-One CAS NO 53951-47-6 is a versatile heterocyclic sulfur compound, specifically a thiolactone derivative, that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a thioxo and a lactone moiety, makes it a valuable precursor for pharmaceuticals, agrochemicals, and functional materials. This high-purity intermediate is essential for researchers and manufacturers in fine chemical, pharmaceutical, and material science industries seeking to develop novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its heterocyclic core contributes to biological activity.
• Material Science: Acts as a monomer or precursor for polymers and functional materials, including conductive polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cyclization reactions, heterocycle formation, and as a scaffold for constructing complex molecular architectures in research and development.
• Chemical Research: Serves as a standard or starting material in academic and industrial laboratories for methodological studies and the synthesis of novel chemical entities.

Basic Information

Product Name	4,5-Dihydro-5-Thioxothiophen-2(3H)-One
CAS No.	53951-47-6
Molecular Formula	C4H4OS2
Molecular Weight	132.20 g/mol
Synonyms	5-Thioxotetrahydrothiophen-2-one; 2(3H)-Thiophenone, 4,5-dihydro-5-thioxo-; 5-Thioxo-2-tetrahydrothiophenone; Tetrahydro-5-thioxo-2-thiophenone; 5-Mercapto-2(3H)-thiophenone; 2-Thiophenecarbothioic acid, tetrahydro-; 4,5-Dihydro-5-thioxo-2(3H)-thiophenone
EINECS	Contact for details

Quality Control

Our production of 4,5-Dihydro-5-Thioxothiophen-2(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic and spectroscopic methods, to verify identity and purity. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.