Description

(4R)-3β,21β-Dihydroxy-C(14A)-Homo-27-Norgammacer-14-En-23-Oic Acid is a high-purity, semi-synthetic triterpenoid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroid-like or triterpenoid-based therapeutic agents.
• Reference Standard: Used in analytical method development and validation for quality control in API (Active Pharmaceutical Ingredient) manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Research: Investigated for its potential interactions with enzymes and receptors relevant to metabolic or inflammatory pathways.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential new chemical entities (NCEs).

Basic Information

Product Name	(4R)-3β,21β-Dihydroxy-C(14A)-Homo-27-Norgammacer-14-En-23-Oic Acid
CAS No.	53755-77-4
Molecular Formula	C29H46O4
Molecular Weight	458.68 g/mol
Synonyms	3β,21β-Dihydroxy-14α-homo-27-norgammacer-14-en-23-oic acid; 27-Norgammacer-14-en-23-oic acid, 3,21-dihydroxy-, (3β,4R,21β)-; 14α-Homo-27-norgammacer-14-en-23-oic acid, 3β,21β-dihydroxy-; (4R)-3β,21β-Dihydroxy-14α-homo-27-norgammacer-14-en-23-oic acid; Triterpenoid acid derivative; Gammacerane derivative.
EINECS	Contact for details

Quality Control

Our (4R)-3β,21β-Dihydroxy-C(14A)-Homo-27-Norgammacer-14-En-23-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.