Description

3-Fluoro-3-Methylbut-1-Yne is a highly versatile fluorinated alkyne building block, prized for its unique reactivity profile. Its value lies in enabling the efficient synthesis of complex fluorinated molecules, which are critical for tuning the physical and biological properties of advanced materials and pharmaceuticals. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorine atoms into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl (CF3) group or other fluorinated motifs into potential drug candidates, enhancing metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where fluorination improves efficacy and environmental profile.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, coatings, and liquid crystals with tailored thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) and other coupling reactions to create complex molecular architectures.
• Fluorine Chemistry Research: An important reagent for academic and industrial research exploring new fluorination methodologies and reaction mechanisms.

Basic Information

Product Name	3-Fluoro-3-Methylbut-1-Yne
CAS No.	53731-17-2
Molecular Formula	C5H7F
Molecular Weight	86.11 g/mol
Synonyms	3-Fluoro-3-methyl-1-butyne; 3-Methyl-3-fluorobut-1-yne; 1-Butyne, 3-fluoro-3-methyl-; 3-Fluoro-3-methylbutyne; 3-Fluoroisopentyne; 3-Methyl-3-fluorobutyne
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-3-Methylbut-1-Yne is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure compliance with agreed specifications and high purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile nature, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent evaporation and potential degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.