Description

Dehydrobruceine B CAS NO 53730-90-8 is a bioactive quassinoid compound, a key intermediate and reference standard derived from the *Brucea* genus of plants. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of antiparasitic and anticancer agents. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of high-grade botanical extracts and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical R&D: Serves as a crucial reference standard and intermediate in the development of novel antiparasitic and anticancer therapeutics.
• Analytical Chemistry: Used as a certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and other analytical techniques.
• Natural Product Isolation: Acts as a target compound for the extraction, purification, and standardization of quassinoids from botanical sources.
• Biological Studies: Employed in in vitro and in vivo studies to investigate mechanisms of action, pharmacokinetics, and toxicity profiles.
• API Manufacturing: Used as a starting material or intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Dehydrobruceine B
CAS No.	53730-90-8
Molecular Formula	C20H26O9
Molecular Weight	410.42 g/mol
Synonyms	Dehydrobruceine B; 13,18-Dehydrobruceine B; NSC 165563; Bruceine derivative; Quassinoid; (1S,2R,12bS)-1,2,12b-Trihydroxy-7-methoxy-3,11-dioxo-1,2,3,11,12,12b-hexahydro-9H-[1]benzoxepino[3,4-b]furo[3,2-h][1]benzopyran-9-yl (2E)-2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our Dehydrobruceine B is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.