Description

Ethanone, 2-Chloro-1-(2-Fluorophenyl)- (9Ci) is a specialized fluorinated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials. Its reliable quality and consistent performance are paramount for ensuring the success of downstream synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers and functional polymers, including liquid crystals and organic semiconductors.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring novel fluorination reactions and heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(2-Fluorophenyl)- (9Ci)
CAS No.	53688-17-8
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-Chloro-1-(2-fluorophenyl)ethanone; 2'-Fluoro-2-chloroacetophenone; 2-Chloro-2'-fluoroacetophenone; α-Chloro-2-fluoroacetophenone; 1-(2-Fluorophenyl)-2-chloroethanone; 2-Fluorophenacyl chloride; NSC 403796; (2-Fluorophenyl)chloromethyl ketone
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 2-Chloro-1-(2-Fluorophenyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to consistent quality and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.