Description

13,20-Epoxy-2,11β,12α-Trihydroxy-15β-[[2-(1-Hydroxyethyl)-3-Methyl-1-Oxo-2-Butenyl]Oxy]-3,16-Dioxopicrasa-1,4-Dien-21-Oic Acid Methyl Ester is a complex, highly functionalized diterpenoid derivative, valued for its intricate molecular architecture which serves as a critical intermediate in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to construct novel bioactive molecules. It is particularly relevant for medicinal chemists and process development scientists working on natural product derivatives and complex synthetic targets.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive compounds derived from natural product scaffolds.
• Process Chemistry Development: Acts as a benchmark or target molecule for developing and optimizing complex multi-step synthetic routes in laboratory and pilot-scale settings.
• Agrochemical Research: Investigated as a precursor for developing new plant growth regulators or bioactive agents with specific modes of action.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in total synthesis, methodology development, and chemical biology.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and identification in related chemical processes.

Basic Information

Product Name	13,20-Epoxy-2,11β,12α-Trihydroxy-15β-[[2-(1-Hydroxyethyl)-3-Methyl-1-Oxo-2-Butenyl]Oxy]-3,16-Dioxopicrasa-1,4-Dien-21-Oic Acid Methyl Ester
CAS No.	53663-02-8
Molecular Formula	C30H38O12
Molecular Weight	590.62 g/mol
Synonyms	Picrasane diterpenoid derivative; Methyl 13,20-epoxy-2,11β,12α-trihydroxy-15β-[[2-(1-hydroxyethyl)-3-methyl-1-oxo-2-butenyl]oxy]-3,16-dioxopicrasa-1,4-dien-21-oate; 2,11β,12α-Trihydroxy-15β-[[2-(1-hydroxyethyl)-3-methyl-1-oxo-2-butenyl]oxy]-13,20-epoxy-3,16-dioxopicrasa-1,4-dien-21-oic acid methyl ester; Nigakilactone F derivative; Quassinoid-related intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 13,20-Epoxy-2,11β,12α-Trihydroxy-15β-[[2-(1-Hydroxyethyl)-3-Methyl-1-Oxo-2-Butenyl]Oxy]-3,16-Dioxopicrasa-1,4-Dien-21-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO-aligned practices for research-grade materials, ensuring reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.