Description

Dehydrobruceantarin is a specialized quassinoid compound, a class of natural products known for their significant biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of novel therapeutic agents. It serves as an essential analytical standard for quality control in the production of botanical extracts and advanced intermediates. Researchers in medicinal chemistry and pharmacology rely on this compound for its defined structure and consistent performance in bioactivity assays.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of bruceantin-related compounds in drug development.
• Medicinal Chemistry Research: Serves as a key intermediate or lead compound in the synthesis and evaluation of new anticancer and antiparasitic agents.
• Botanical Extract Standardization: Employed in the quality control of herbal extracts, such as those from *Brucea* species, to ensure batch-to-batch consistency and potency.
• Biological Activity Screening: Utilized in in vitro and in vivo studies to investigate its cytotoxic, anti-inflammatory, or other pharmacological properties.
• Academic and Institutional Research: Provides a well-characterized compound for university and government lab studies on natural product chemistry and bioactivity.
• Analytical Method Development: Acts as a critical component in developing and validating HPLC, LC-MS, or other chromatographic methods for quassinoid analysis.

Basic Information

Product Name	Dehydrobruceantarin
CAS No.	53663-00-6
Molecular Formula	C28H34O11
Molecular Weight	546.57 g/mol
Synonyms	Bruceantin, Dehydro; 13,18-Dehydrobruceantin; NSC-325319; (1S,2R,5S,7S,10R,11S,14S,15R)-5-(Acetyloxy)-14-[(2S,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-[(1S)-1-methyl-2-oxoethoxy]oxan-2-yl]oxy-2,11,12-trihydroxy-7,15-dimethyl-6-oxapentacyclo[9.7.0.01,14.02,7.011,15]octadec-12-ene-4,8,16-trione
EINECS	Contact for details

Quality Control

Our Dehydrobruceantarin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, identity, and purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.