Description

Dehydrobruceantin is a bioactive quassinoid compound derived from plants of the genus *Brucea*, known for its potent and selective biological activity. This high-purity compound is critical for pharmaceutical research and development, particularly in the fields of oncology and parasitology. It serves as a valuable reference standard and a key intermediate for researchers and manufacturers in the life sciences sector seeking to develop novel therapeutic agents.

Application

• Pharmaceutical R&D Intermediate: Serves as a key building block in the synthesis of novel anti-cancer and anti-parasitic drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biological Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms of apoptosis, cell cycle arrest, and anti-angiogenic effects.
• Natural Product Chemistry: Acts as a purified marker compound for the standardization of botanical extracts, such as those from *Brucea javanica*.
• Preclinical Studies: Utilized in pharmacokinetic, pharmacodynamic, and toxicology profiling of new therapeutic entities.

Basic Information

Product Name	Dehydrobruceantin
CAS No.	53662-98-9
Molecular Formula	C₂₀H₂₈O₉
Molecular Weight	412.43 g/mol
Synonyms	Dehydrobruceantin; NSC-165563; Bruceantin, 13,18-dehydro-; 13,18-Dehydrobruceantin; (1S,2R,4aS,6aS,6bR,8R,10aS,12aS,12bR,14bS)-8-(Furan-3-yl)-1,2,6a,8,10a,12a-hexahydroxy-1,4a,6b,11,11,14b-hexamethyl-3,4,5,6,6a,7,9,10,12,12b,13,14-dodecahydro-2H-picene-2,10-dione
EINECS	Contact for details

Quality Control

Our Dehydrobruceantin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storage under inert atmosphere at -20°C. The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.