Description

2-Chloro-5-Trifluoromethyl-1,3,4-Thiadiazole is a versatile and highly functionalized heterocyclic building block. Its unique structure, featuring both chloro and trifluoromethyl substituents on a thiadiazole core, makes it a critical intermediate for synthesizing advanced molecules with tailored properties. This compound is essential for R&D and production chemists in the agrochemical and pharmaceutical industries seeking to introduce fluorine and heterocyclic motifs into their target compounds.

Application

• Agrochemical Intermediate: A key precursor for the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Pharmaceutical Building Block: Used in medicinal chemistry to create potential drug candidates, particularly for developing active pharmaceutical ingredients (APIs) with improved bioavailability and selectivity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced materials with specific electronic or surface properties.
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and functional colorants where the thiadiazole ring contributes to color fastness and unique chromophoric properties.
• Ligand and Catalyst Development: Useful for constructing complex ligands in coordination chemistry and catalysis, leveraging the nitrogen and sulfur atoms for metal binding.

Basic Information

Item	Details
Product Name	2-Chloro-5-Trifluoromethyl-1,3,4-Thiadiazole
CAS No.	53645-98-0
Molecular Formula	C3ClF3N2S
Molecular Weight	188.58 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)-1,3,4-thiadiazole; 5-(Trifluoromethyl)-2-chloro-1,3,4-thiadiazole; 1,3,4-Thiadiazole, 2-chloro-5-(trifluoromethyl)-; CTFT; 2-Chloro-α,α,α-trifluoro-1,3,4-thiadiazole-5-methane
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Trifluoromethyl-1,3,4-Thiadiazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.