Description

2-Piperidinone, 4-(Hydroxymethyl)- is a versatile heterocyclic building block featuring both a lactam and a hydroxymethyl functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery, active ingredient synthesis, and the creation of novel polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of piperidine-based compounds with potential neurological or therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and plant growth regulators that require the piperidinone scaffold.
• Fine Chemical Building Block: Serves as a versatile precursor in organic synthesis for creating complex molecules used in material science, dyes, and specialty chemicals.
• Polymer Modification: The hydroxymethyl group allows for incorporation into polymer chains, enabling the creation of specialty polyamides or functionalized materials with tailored properties.
• Biochemical Research: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and as a scaffold in combinatorial chemistry libraries.
• Ligand and Catalyst Development: Useful for synthesizing novel chelating ligands or organocatalysts due to its nitrogen and oxygen donor atoms.

Basic Information

Product Name	2-Piperidinone, 4-(Hydroxymethyl)-
CAS No.	53611-47-5
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	4-(Hydroxymethyl)piperidin-2-one; 4-(Hydroxymethyl)-2-piperidinone; 4-Hydroxymethyl-2-piperidone; 4-Piperidinol, 2-oxo-, (4R)-; 4-(Hydroxymethyl)-2-piperidone; 2-Oxo-4-piperidinemethanol; 4-Hydroxymethyl-δ-valerolactam
EINECS	Contact for details

Quality Control

Our 2-Piperidinone, 4-(Hydroxymethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.