Description

(S)-5-[(4-Amino-4-Carboxy-1-Oxobutyl)Amino]-2-Nitrobenzoic Acid is a specialized chiral organic compound with a defined stereochemistry, serving as a critical building block in advanced chemical synthesis. Its value lies in its role as a high-purity intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise molecular architecture. This product is essential for research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors engaged in the synthesis of novel therapeutic agents and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel Active Pharmaceutical Ingredients (APIs), particularly for targeted therapies.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive amino and carboxyl functional groups.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design and synthesis of peptide mimetics for drug discovery programs.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Agrochemical Synthesis: Acts as a precursor in the development of advanced, high-specificity agrochemicals and plant growth regulators.
• Material Science: A potential monomer or cross-linking agent for creating functional polymers with specific optical or chemical properties.

Basic Information

Product Name	(S)-5-[(4-Amino-4-Carboxy-1-Oxobutyl)Amino]-2-Nitrobenzoic Acid
CAS No.	53602-84-9
Molecular Formula	C12H13N3O7
Molecular Weight	311.25 g/mol
Synonyms	(S)-2-Nitro-5-[(4-amino-4-carboxybutanoyl)amino]benzoic Acid; L-γ-Glutamyl-2-nitro-5-aminobenzoic Acid; 5-[(S)-4-Amino-4-carboxybutyramido]-2-nitrobenzoic Acid; 2-Nitro-5-[(S)-4-amino-4-carboxybutyramido]benzoic Acid; (S)-5-(4-Amino-4-carboxybutanamido)-2-nitrobenzoic Acid; A Chiral Glutamate Derivative; A Nitroaniline Benzoic Acid Derivative
EINECS	Contact for details

Quality Control

Our (S)-5-[(4-Amino-4-Carboxy-1-Oxobutyl)Amino]-2-Nitrobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.