Description

1,3,5-Triaza-7-Phosphatricyclo[3.3.1.13,7]Decane, 7-Oxide is a highly versatile and stable heterocyclic organophosphorus compound, also known as Verkade's superbase. Its unique structure provides exceptional basicity and nucleophilicity, making it a valuable catalyst and ligand in advanced organic synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-performance, non-ionic bases for demanding reactions.

Application

• Catalyst in Organic Synthesis: Acts as a powerful, non-nucleophilic base for deprotonation reactions, alkylations, and condensations.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, particularly where mild and selective basic conditions are required.
• Ligand for Transition Metal Complexes: Forms stable complexes with metals like palladium and platinum for use in cross-coupling and hydrogenation catalysis.
• Polymerization Catalyst: Employed as an initiator or co-catalyst in the production of specialized polymers and resins.
• Agrochemical Synthesis: Facilitates the manufacture of advanced pesticides and herbicides through key intermediate reactions.
• Research & Development: A critical reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	1,3,5-Triaza-7-Phosphatricyclo[3.3.1.13,7]Decane, 7-Oxide
CAS No.	53597-70-9
Molecular Formula	C6H12N3OP
Molecular Weight	173.15 g/mol
Synonyms	Verkade's Superbase; 1,3,5-Triaza-7-phosphatricyclo[3.3.1.13,7]decane 7-oxide; 7-Oxo-1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane; P(O)N3Me6; Proazaphosphatrane; 2,4,6-Trimethyl-1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane 7-oxide; Hexamethyltriaminophosphine Oxide; HMPTO; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 1,3,5-Triaza-7-Phosphatricyclo[3.3.1.13,7]Decane, 7-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	285 - 295 °C (dec.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.