Description

1-(2',4'-Difluoro[1,1'-Biphenyl]-4-Yl)Ethan-1-One is a high-purity fluorinated biphenyl ketone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which enables the construction of complex molecules with enhanced properties for demanding applications. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce specific fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluorobiphenyl moiety can enhance activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer & Specialty Chemicals: Acts as a monomer or modifier in the synthesis of high-performance polymers, coatings, and specialty chemicals requiring specific aromatic fluorination.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on cross-coupling reactions, medicinal chemistry, and material science explorations.

Basic Information

Product Name	1-(2',4'-Difluoro[1,1'-Biphenyl]-4-Yl)Ethan-1-One
CAS No.	53591-79-0
Molecular Formula	C14H10F2O
Molecular Weight	232.23 g/mol
Synonyms	4'-Acetyl-2,4-difluorobiphenyl; 1-(2,4-Difluorobiphenyl-4-yl)ethanone; 2',4'-Difluoro-4-acetylbiphenyl; 4-Acetyl-2',4'-difluorobiphenyl; 1-[4-(2,4-Difluorophenyl)phenyl]ethanone; Ethanone, 1-[1,1'-biphenyl]-4-yl-2,4-difluoro-
EINECS	Contact for details

Quality Control

Our production of 1-(2',4'-Difluoro[1,1'-Biphenyl]-4-Yl)Ethan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.