Description

4-Hydroxy-1,5-Naphthyridine-3-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused-ring structure with both carboxylic acid and hydroxyl functionalities makes it a valuable intermediate for creating complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive heterocyclic core.
• Ligand Synthesis: Serves as a chelating agent or ligand precursor in coordination chemistry and catalyst design for industrial processes.
• Material Science: A building block for creating specialty polymers, dyes, or organic electronic materials with specific optical properties.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical reactions.
• Fine Chemical Production: Integrated into multi-step synthesis pathways for producing high-value, complex specialty chemicals.

Basic Information

Item	Details
Product Name	4-Hydroxy-1,5-Naphthyridine-3-Carboxylic Acid
CAS No.	53512-10-0
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	1,5-Naphthyridin-4-ol-3-carboxylic acid; 3-Carboxy-4-hydroxy-1,5-naphthyridine; 4-Hydroxy-1,5-naphthyridine-3-carboxylic acid; 1,5-Naphthyridine-3-carboxylic acid, 4-hydroxy-; 4-Hydroxy-[1,5]naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Hydroxy-1,5-Naphthyridine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.