Description

8,8A-Deoxyoleandolide CAS NO 53428-54-9 is a specialized macrolide compound of significant interest in advanced chemical synthesis and pharmaceutical research. Its unique structural framework makes it a valuable intermediate for developing novel therapeutic agents and studying complex molecular interactions. This high-purity chemical is essential for research institutions and pharmaceutical companies focused on antibiotic development, chemical biology, and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel macrolide antibiotics and other bioactive molecules.
• Medicinal Chemistry Research: Used as a reference standard and precursor in structure-activity relationship (SAR) studies for drug discovery programs.
• Chemical Biology: Employed as a molecular probe to investigate biological pathways and enzyme interactions.
• Academic & Industrial R&D: Serves as a critical reagent for synthetic organic chemists exploring complex natural product synthesis.
• Reference Standard: Utilized in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	8,8A-Deoxyoleandolide
CAS No.	53428-54-9
Molecular Formula	C32H48O8
Molecular Weight	560.73 g/mol
Synonyms	8,8a-Dideoxyoleandolide; 8-Deoxy-8a-deoxyoleandolide; Oleandolide, 8,8a-dideoxy-; (3R,5R,8R,9S,10R,11R,13R,14S)-14-Ethyl-7,12,13-trihydroxy-3,5,9,11-tetramethyl-4-oxo-oxacyclotetradecane-2,6-dione; Macrolide L-121,212; Antibiotic L-121,212
EINECS	Contact for details

Quality Control

Every batch of 8,8A-Deoxyoleandolide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products meet high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.