Description

Fluoromethyl(Pentafluorophenyl)Phosphine Oxide is a specialized organophosphorus compound featuring a unique combination of fluorinated alkyl and aryl groups. This structure makes it a valuable intermediate and ligand in advanced synthetic chemistry, particularly for applications requiring high thermal stability and resistance to oxidation. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides with improved efficacy and environmental profiles.
• Ligand in Catalysis: Serves as a precursor for phosphine ligands in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck reactions).
• Flame Retardant Synthon: Incorporated into polymers and coatings to enhance flame retardancy due to its phosphorus and fluorine content.
• Electronic Materials: Investigated for use in the synthesis of organic semiconductors and electrolyte additives for lithium-ion batteries.
• Organic Synthesis Reagent: Employed in fluorination reactions and as a stabilizing agent for sensitive organometallic complexes.

Basic Information

Product Name	Fluoromethyl(Pentafluorophenyl)Phosphine Oxide
CAS No.	53381-00-3
Molecular Formula	C7H2F6OP
Molecular Weight	244.06 g/mol
Synonyms	Fluoromethyl(pentafluorophenyl)phosphine oxide; (Pentafluorophenyl)(fluoromethyl)phosphine oxide; Fluoromethyl-pentafluorophenyl-phosphine oxide; (Fluoromethyl)(pentafluorophenyl)phosphine oxide; Pentafluorophenylfluoromethylphosphine oxide; FC6P(O)CH2F; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of Fluoromethyl(Pentafluorophenyl)Phosphine Oxide is manufactured and tested under strict quality management protocols. We ensure product integrity through comprehensive analytical techniques including NMR, HPLC, and GC-MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.