Description

Menthyl Borate CAS NO 53370-45-9 is a specialized organoboron compound derived from menthol. This chemical is valued for its role as a chiral intermediate and reagent in sophisticated organic synthesis, particularly in the pharmaceutical and fine chemical sectors. It is essential for manufacturers and R&D laboratories seeking to introduce boronate functionality or leverage its stereochemical properties for producing high-value, optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Cross-Coupling Reactions: Acts as a boron reagent in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Research & Development: Employed in academic and industrial R&D for methodological development and exploring new synthetic pathways.
• Flavor & Fragrance Chemistry: Used in the synthesis of novel or high-value aroma chemicals and flavoring agents.

Basic Information

Product Name	Menthyl Borate
CAS No.	53370-45-9
Molecular Formula	C10H19BO3 (commonly represented for the core structure; exact formula may vary based on hydration/ester form)
Molecular Weight	Contact for details
Synonyms	Menthyl Borate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Borate; Boric Acid, Menthyl Ester; Menthol Borate; L-Menthyl Borate; (-)-Menthyl Borate; Boron Menthoxide; Menthyl Boronate
EINECS	Contact for details

Quality Control

Our Menthyl Borate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment and impurity profiling. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.