Description

Trans,trans-Bis(4-Fluorobenzylidene)Acetone (CAS NO 53369-00-9) is a high-purity fluorinated organic building block characterized by its conjugated bis-benzylideneacetone structure. This compound matters for its role as a key intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific stereochemistry and fluorine atoms are critical for performance. Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty polymer production need this chemical for developing new compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms can improve bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a core building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Polymer Cross-linking Agent: Employed in the production of specialty polymers and resins, where it can introduce rigidity and specific optical properties into the polymer matrix.
• Organic Synthesis & Research: A valuable reagent in academic and industrial research labs for Diels-Alder reactions, Michael additions, and the construction of complex polycyclic structures.
• Fluorescent Dye & Sensor Development: Utilized in the creation of fluorophores and chemical sensors, leveraging its extended conjugated pi-system for light absorption and emission.

Basic Information

Product Name	Trans,trans-Bis(4-Fluorobenzylidene)Acetone
CAS No.	53369-00-9
Molecular Formula	C17H12F2O
Molecular Weight	270.27 g/mol
Synonyms	1,5-Bis(4-Fluorophenyl)-1,4-pentadien-3-one; (E,E)-1,5-Bis(4-fluorophenyl)penta-1,4-dien-3-one; Di-4-fluorobenzylideneacetone; (E,E)-1,5-Di(4-fluorophenyl)-1,4-pentadien-3-one; 4,4'-(1E,4E)-1,4-Pentadiene-1,5-diylbis(fluorobenzene); Bis(4-fluorobenzylidene)acetone; DFBA; tt-Bis(4-Fluorobenzylidene)Acetone
EINECS	Contact for details

Quality Control

Our Trans,trans-Bis(4-Fluorobenzylidene)Acetone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	142 - 148 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.