Description

Cyclobutyl 4-Trifluoromethylphenyl Ketone is a high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique structure, featuring a cyclobutyl ring and a trifluoromethylphenyl group, makes it a critical intermediate for creating novel compounds with tailored properties. This product is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and chemical resistance.
• Chemical Synthesis Reagent: Employed in organic reactions such as Friedel-Crafts acylation and Grignard reactions to introduce the cyclobutyl ketone moiety.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	Cyclobutyl 4-Trifluoromethylphenyl Ketone
CAS No.	53342-40-8
Molecular Formula	C12H11F3O
Molecular Weight	228.21 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)cyclobutan-1-one; 4-Trifluoromethyl Cyclobutyl Phenyl Ketone; Cyclobutyl(4-(trifluoromethyl)phenyl)methanone; p-(Trifluoromethyl)cyclobutyl phenyl ketone; α-Cyclobutyl-4-(trifluoromethyl)acetophenone; 4'-Trifluoromethylcyclobutyl phenyl ketone; Ketone, cyclobutyl 4-trifluoromethylphenyl
EINECS	Contact for details

Quality Control

Our Cyclobutyl 4-Trifluoromethylphenyl Ketone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.