Description

Ethyl 3-[n-(Phenyl)Amino]-3-Oxopropionate is a versatile β-keto ester derivative that serves as a critical synthetic intermediate in organic chemistry. Its value lies in its bifunctional reactivity, featuring both an active methylene group and an ester moiety, enabling its use in various condensation and cyclization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for synthesizing heterocyclic compounds, fine chemicals, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various heterocyclic compounds, including pyrazoles, pyrimidines, and quinolones, which are core structures in many drug molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its reactivity to create complex molecular architectures.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring specific β-keto ester functionalities.
• Academic & R&D: A valuable reagent in research laboratories for method development, catalysis studies, and exploring new organic synthetic pathways.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with tailored properties.

Basic Information

Product Name	Ethyl 3-[n-(Phenyl)Amino]-3-Oxopropionate
CAS No.	53341-66-5
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	Ethyl 3-(Phenylamino)-3-oxopropanoate; Ethyl (Phenylcarbamoyl)acetate; N-Phenylmalonamic Acid Ethyl Ester; 3-Oxo-3-(phenylamino)propanoic Acid Ethyl Ester; Acetoacetic Acid N-Phenylamide Ethyl Ester; Ethyl 3-(Anilino)-3-oxopropanoate; Ethyl β-Anilinocrotonate (tautomeric form); NSC 163022
EINECS	Contact for details

Quality Control

Our Ethyl 3-[n-(Phenyl)Amino]-3-Oxopropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.