Description

(59S)-57-Demethyl-45-De(2-Methyl-1-Oxopropyloxy)-59-Deoxo-59-Methoxy-45-Methoxy-12-o-(3-C,4-o-Dimethyl-3-Nitro-2,3,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Flambamycin is a structurally complex, semi-synthetic derivative of the flambamycin antibiotic class, representing a key intermediate in advanced pharmaceutical research. Its value lies in its role as a critical building block for developing novel therapeutic agents, particularly in the exploration of next-generation antibiotics and anti-cancer compounds. This high-purity chemical is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel antibiotic candidates targeting resistant bacterial strains.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Anti-cancer Agent Development: Investigated for its potential as a starting material in the synthesis of compounds with cytotoxic activity.
• Biochemical Tool Compound: Employed in microbiological and enzymatic assays to study mechanisms of action related to its parent compound class.
• Process Chemistry & Scale-up: Utilized in developing and optimizing synthetic routes for the production of complex bioactive molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Item	Details
Product Name	(59S)-57-Demethyl-45-De(2-Methyl-1-Oxopropyloxy)-59-Deoxo-59-Methoxy-45-Methoxy-12-o-(3-C,4-o-Dimethyl-3-Nitro-2,3,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Flambamycin
CAS No.	53296-30-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Flambamycin derivative 53296-30-3; 59-Deoxo-59-methoxyflambamycin derivative; 12-O-(3-C,4-O-Dimethyl-3-nitro-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)flambamycin; Demethyl-deoxo-methoxyflambamycin; Antibiotic U-62162 derivative; 45,59-Di-O-methyl-12-O-(dimethylnitrodeoxyhexopyranosyl)flambamycin; Nitro-sugar conjugated flambamycin analog
EINECS	Contact for details

Quality Control

Our (59S)-57-Demethyl-45-De(2-Methyl-1-Oxopropyloxy)-59-Deoxo-59-Methoxy-45-Methoxy-12-o-(3-C,4-o-Dimethyl-3-Nitro-2,3,6-Trideoxy-α-L-Arabino-Hexopyranosyl)Flambamycin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.