Description

(22E)-3β-[(Trimethylsilyl)Oxy]-5α-Ergosta-7,22-Dien-6-One o-Methyl Oxime is a high-purity, sterol-derived chemical intermediate featuring a strategically protected oxime functional group. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures in pharmaceutical research and development. It is primarily sought after by R&D laboratories and manufacturers in the life sciences sector for use as a key building block in the synthesis of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a derivatized probe in metabolic pathway studies and sterol biochemistry research.
• Organic Synthesis Building Block: The protected oxime and silyl ether groups make it a versatile synthon for constructing complex natural product analogs and specialty chemicals.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories.

Basic Information

Product Name	(22E)-3β-[(Trimethylsilyl)Oxy]-5α-Ergosta-7,22-Dien-6-One o-Methyl Oxime
CAS No.	53286-61-6
Molecular Formula	C32H55NO2Si
Molecular Weight	513.88 g/mol
Synonyms	5α-Ergosta-7,22-dien-6-one, 3-[(trimethylsilyl)oxy]-, O-methyloxime, (3β,22E)-; (22E)-3β-[(Trimethylsilyl)oxy]ergosta-7,22-dien-6-one O-methyloxime; 3β-Trimethylsiloxy-5α-ergosta-7,22-dien-6-one O-methyloxime; Ergosta-7,22-dien-6-one O-methyloxime TMS ether; Sterol oxime TMS ether derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (22E)-3β-[(Trimethylsilyl)Oxy]-5α-Ergosta-7,22-Dien-6-One o-Methyl Oxime is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.