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2,3-Oxiranedicarboxylic Acid, 2-Methyl-, Dimethyl Ester,(2R,3R)-Rel- CAS NO 53282-74-9


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CAS No.:53282-74-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3-Oxiranedicarboxylic Acid, 2-Methyl-, Dimethyl Ester,(2R,3R)-Rel- is a high-purity chiral epoxide derivative, a crucial building block in asymmetric synthesis. Its defined stereochemistry and reactive oxirane ring make it an invaluable intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
  • Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical Production: Serves as a precursor for specialty chemicals, including advanced polymers, liquid crystals, and chiral ligands for catalysis.
  • Asymmetric Catalysis Research: Employed in academic and industrial R&D for developing and testing new asymmetric synthetic methodologies.
  • Flavor and Fragrance Industry: Potential intermediate for creating specific chiral aroma compounds.

Basic Information

Product Name 2,3-Oxiranedicarboxylic Acid, 2-Methyl-, Dimethyl Ester,(2R,3R)-Rel-
CAS No. 53282-74-9
Molecular Formula C8H12O5
Molecular Weight 188.18 g/mol
Synonyms (2R,3R)-2-Methyl-2,3-epoxysuccinic Acid Dimethyl Ester; Dimethyl (2R,3R)-2-Methyloxirane-2,3-dicarboxylate; rel-(2R,3R)-2-Methyl-2,3-epoxysuccinic Acid Dimethyl Ester; (R,R)-2-Methyl-2,3-epoxysuccinic Acid Dimethyl Ester; 2-Methyl-2,3-epoxysuccinic Acid Dimethyl Ester (rel-(2R,3R)-form); Methyl Epoxysuccinate Derivative
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Quality Control

Our production of 2,3-Oxiranedicarboxylic Acid, 2-Methyl-, Dimethyl Ester,(2R,3R)-Rel- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric excess (e.e.). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We operate in compliance with cGMP standards where applicable, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% e.e. (2R,3R)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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