Description

Dibenzylphosphonoacetic Acid CAS NO 53243-58-6 is a versatile organophosphorus compound characterized by its phosphonoacetic acid core protected by benzyl groups. This structure makes it a valuable building block and reagent in synthetic organic chemistry, particularly for the preparation of phosphonate esters and other functionalized molecules. It is primarily utilized by pharmaceutical intermediates, agrochemical research, and specialty chemical manufacturers seeking to introduce phosphonate functionality into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs containing phosphonate or bisphosphonate groups.
• Agrochemical Synthesis: Building block for creating novel herbicides, plant growth regulators, and other crop protection agents with phosphonate moieties.
• Ligand and Catalyst Preparation: Used to synthesize specialized phosphonate-based ligands for metal catalysis and coordination chemistry.
• Peptide Mimetics and Bioisosteres: Employed in medicinal chemistry to create phosphonate analogs of amino acids or peptides, altering biological activity and stability.
• Material Science Research: Monomer or additive for developing functional polymers, surface modifiers, or flame retardants.
• Chemical Biology Probes: Serves as a starting material for creating activity-based probes or enzyme inhibitors targeting phosphatases and related enzymes.

Basic Information

Item	Detail
Product Name	Dibenzylphosphonoacetic Acid
CAS No.	53243-58-6
Molecular Formula	C16H17O5P
Molecular Weight	320.28 g/mol
Synonyms	Dibenzyl (carboxymethyl)phosphonate; (Dibenzoxyphosphinyl)acetic Acid; Acetic acid, 2-(dibenzylphosphinyl)-; Phosphonoacetic Acid, Dibenzyl Ester; DBPA; Dibenzyl PAA; 2-(Dibenzylphosphoryl)acetic Acid
EINECS	Contact for details

Quality Control

Our Dibenzylphosphonoacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Standard quality parameters include assay (by titration or HPLC), identification (IR, NMR), and control of key impurities. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.