Description

Tris(Dimethylamino)(Trimethylsilylimino)Phosphorane is a highly reactive, specialized organophosphorus reagent featuring a unique silylimino group. This compound is valued for its role as a powerful base and nucleophile in demanding synthetic transformations, particularly for the formation of carbon-nitrogen and carbon-phosphorus bonds. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, performance-driven reagents for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of novel pesticides and herbicides, leveraging its reactivity to create specific phosphorane-based structures.
• Polymer & Materials Science: Employed as a monomer or catalyst in the production of specialty polymers and advanced materials with tailored properties.
• Peptide & Nucleotide Chemistry: Facilitates condensation reactions and the synthesis of phosphoramidite derivatives for oligonucleotide production.
• Academic & Industrial R&D: Serves as a versatile building block in methodological development and the discovery of new chemical entities.
• Catalyst & Ligand Precursor: Acts as a starting material for generating novel phosphorus-based ligands used in homogeneous catalysis.

Basic Information

Product Name	Tris(Dimethylamino)(Trimethylsilylimino)Phosphorane
CAS No.	53167-50-3
Molecular Formula	C9H27N4PSi
Molecular Weight	250.40 g/mol
Synonyms	Tris(dimethylamino)(trimethylsilylimino)phosphorane; (Trimethylsilylimino)tris(dimethylamino)phosphorane; Phosphorane, tris(dimethylamino)(trimethylsilylimino)-; Tris(dimethylamino)(trimethylsilylimino)phosphorus; P(NMe2)3(NSiMe3); TAS-F Reagent Analog
EINECS	Contact for details

Quality Control

Our Tris(Dimethylamino)(Trimethylsilylimino)Phosphorane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by advanced analytical techniques, including NMR and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Due to its hygroscopic and moisture-sensitive nature, the container must be handled and opened under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.