Description

5-tert-Butyl-1,3-Benzoxazole-2-Thiol is a specialized heterocyclic organic compound featuring a benzoxazole core functionalized with a tert-butyl group and a thiol moiety. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in the fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the benzoxazole-thiol structure can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a chelating agent or ligand precursor in organometallic chemistry for creating catalysts used in cross-coupling and other synthetic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs or conductive polymers, due to its electron-rich heterocyclic system.
• Chemical Biology Probe: Utilized in biochemical research to develop probes or inhibitors that interact with specific enzymes or biological pathways.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and custom synthesis manufacturers to create complex, tailor-made molecules for client projects.

Basic Information

Product Name	5-tert-Butyl-1,3-Benzoxazole-2-Thiol
CAS No.	53146-48-8
Molecular Formula	C11H13NOS
Molecular Weight	207.29 g/mol
Synonyms	2-Mercapto-5-tert-butylbenzoxazole; 5-tert-Butyl-2-mercaptobenzoxazole; 5-(1,1-Dimethylethyl)-2-benzoxazolethiol; 2-Benzoxazolethiol, 5-(1,1-dimethylethyl)-; 5-tert-Butyl-2-benzoxazolyl mercaptan; 5-tert-Butylbenzo[d]oxazole-2-thiol; 2(3H)-Benzoxazolethione, 5-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-tert-Butyl-1,3-Benzoxazole-2-Thiol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.