Description

4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Methyl Ester is a high-purity biphenyl derivative ester, serving as a critical advanced intermediate in the synthesis of complex organic molecules. Its value lies in its defined molecular architecture, which provides a versatile scaffold for constructing active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel therapeutic agents, particularly in constructing biphenyl-based molecular frameworks.
• Agrochemical Synthesis: Used in the production pathway for advanced crop protection agents and herbicides.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational component in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex molecules via coupling, esterification, and functional group transformation reactions.
• Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other performance chemicals requiring specific biphenyl structures.

Basic Information

Product Name	4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Methyl Ester
CAS No.	53136-99-5
Molecular Formula	C15H13ClO3
Molecular Weight	276.71 g/mol
Synonyms	Methyl 4'-Chloro-5-hydroxybiphenyl-3-acetate; 3-(4-Chlorophenyl)-5-hydroxy-2-methylbenzoic acid methyl ester; 5-Hydroxy-4'-chlorobiphenyl-3-acetic acid methyl ester; Biphenyl-3-acetic acid, 4'-chloro-5-hydroxy-, methyl ester; Methyl (4'-chloro-5-hydroxy-[1,1'-biphenyl]-3-yl)acetate
EINECS	Contact for details

Quality Control

Our 4'-Chloro-5-Hydroxy-(1,1'-Biphenyl)-3-Acetic Acid Methyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.