Description

2-Chloro-1-(2-Hydroxyphenyl)-Ethanone is a versatile aromatic ketone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a phenolic hydroxyl and a reactive α-chloro ketone group, makes it a valuable building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various bioactive molecules, including potential benzofuran and chromone derivatives with therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, nucleophilic substitution, and cyclization reactions to create complex organic structures.
• Dye and Pigment Manufacturing: Intermediate for the production of specialized dyes and optical materials.
• Chemical Research (R&D): A valuable reagent in academic and industrial laboratories for methodological studies and novel compound library generation.
• Coordination Chemistry: Can act as a ligand precursor for metal complexes due to its phenolic oxygen and carbonyl group.

Basic Information

Product Name	2-Chloro-1-(2-Hydroxyphenyl)-Ethanone
CAS No.	53074-73-0
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	2'-Hydroxyphenacyl Chloride; 2-Chloro-1-(2-hydroxyphenyl)ethanone; 1-(2-Hydroxyphenyl)-2-chloroethanone; o-Hydroxyphenacyl Chloride; 2-Chloro-2'-hydroxyacetophenone; Phenacyl Chloride, 2'-hydroxy-; NSC 163082; α-Chloro-2-hydroxyacetophenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2-Hydroxyphenyl)-Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.